For missing persons detectives, if they don�t find the person in the first 48 hours, their chances of finding them alive are cut in half. Based in the heart of one of the country's most colorful law-enforcement cities, the Chicago missing persons unit gets over 17,000 calls each year, and is one of the only police forces in the country that responds to every missing persons call immediately. "The First 48: Missing Persons" follows the elite, passionate, dedicated investigators who handle all missing persons and child abduction cases, men and women who are specially trained to deal with the nuances of their cases which often involve children. Their commitment to solving these cases is unmatched. The First 48: Missing Persons will follow a core group of detectives as they investigate two high-stakes cases per episode. This is the first time ever the Chicago Police have given a film crew unrestricted access to ongoing investigations.